Grey's Anatomy How to Save a Life (Season 11, Episode 21)
TV-14
TV Episode | 43 min | Drama, Romance

Grey's Anatomy

How to Save a Life (Season 11, Episode 21)

TV-14

TV Episode | 43 min | Drama, Romance

Derek witnesses a horrible car crash and jumps in to save lives.

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Cast	+ Add Cast
33 cast members

Name	Known for
Ellen Pompeo Dr. Meredith Grey Dr. Meredith Grey See fewer	Grey's Anatomy (2005)
Justin Chambers Dr. Alex Karev (credit only) Dr. Alex Karev (credit only) See fewer	Grey's Anatomy (2005)
Chandra Wilson Dr. Miranda Bailey Dr. Miranda Bailey See fewer	Grey's Anatomy (2005)
James Pickens Jr. Dr. Richard Webber (credit only) Dr. Richard Webber (credit only) See fewer	Grey's Anatomy (2005)
Sara Ramirez Dr. Callie Torres (credit only) Dr. Callie Torres (credit only) See fewer	Grey's Anatomy (2005)
Kevin McKidd Dr. Owen Hunt Dr. Owen Hunt See fewer	Trainspotting (1996)
Jessica Capshaw Dr. Arizona Robbins (credit only) Dr. Arizona Robbins (credit only) See fewer	Valentine (2001)
Sarah Drew Dr. April Kepner Dr. April Kepner See fewer	Moms' Night Out (2014)
Jesse Williams Dr. Jackson Avery (credit only) Dr. Jackson Avery (credit only) See fewer	The Cabin in the Woods (2011)
Caterina Scorsone Dr. Amelia Shepherd Dr. Amelia Shepherd See fewer	The November Man (2014)
Camilla Luddington Dr. Jo Wilson (credit only) Dr. Jo Wilson (credit only) See fewer	Tomb Raider (2013)
Jerrika Hinton Dr. Stephanie Edwards (credit only) Dr. Stephanie Edwards (credit only) See fewer	Hunters (2020)
Kelly McCreary Dr. Maggie Pierce (credit only) Dr. Maggie Pierce (credit only) See fewer	Grey's Anatomy (2005)
Patrick Dempsey Dr. Derek Shepherd Dr. Derek Shepherd See fewer	Grey's Anatomy (2005)
Larry Cedar Dr. Cohn Dr. Cohn See fewer	Deadwood (2004)
Mike McColl Paul (as Michael McColl) Paul (as Michael McColl) See fewer	Homeland (2011)
Samantha Sloyan Dr. Penelope Blake Dr. Penelope Blake See fewer	Midnight Mass (2021)
Allie Grant Alana Alana See fewer	Fanboys (2009)
Savannah Paige Rae Winnie Winnie See fewer	Parenthood (2010)
Che Landon Sarah Sarah See fewer	Grey's Anatomy (2005)
Robby Rasmussen Charlie Abbott Charlie Abbott See fewer	The Best of Me (2014)
Scott Rinker Toby (as Scott Allen Rinker) Toby (as Scott Allen Rinker) See fewer	Station 19 (2018)
Ashlee Brian Paramedic Jamal Paramedic Jamal See fewer	The Butcher's Ballet
John Eddins Firefighter Firefighter See fewer	The Terminal (2004)
Thomas Owen Police Officer Police Officer See fewer	NCIS: New Orleans (2014)
Terrence Edwards Paramedic Calvin Paramedic Calvin See fewer	Code Black (2015)
Jennifer Aquino Anesthesiologist Anesthesiologist See fewer	Grey's Anatomy (2005)
Irene Park Paramedic #1 Paramedic #1 See fewer	Grey's Anatomy (2005)
Joe Raffa OR Nurse OR Nurse See fewer	Downeast (2021)
Cassidy Brown Nurse Nurse See fewer	Applebaum (2012)
Jael Moore Zola Zola See fewer	Grey's Anatomy (2005)
Bokhee An Nurse Bokhee (uncredited) Nurse Bokhee (uncredited) See fewer	Grey's Anatomy (2005)
Andra Petru Passenger (uncredited) Passenger (uncredited) See fewer	Entourage (2015)