Name	Known for
Iain Armitage Sheldon Cooper Sheldon Cooper See fewer	Young Sheldon (2017)
Zoe Perry Mary Cooper Mary Cooper See fewer	Young Sheldon (2017)
Lance Barber George Cooper Sr. George Cooper Sr. See fewer	Gangster Squad (2013)
Montana Jordan Georgie Cooper Georgie Cooper See fewer	Young Sheldon (2017)
Raegan Revord Missy Cooper Missy Cooper See fewer	Young Sheldon (2017)
Matt Hobby Jeff Difford Jeff Difford See fewer	Young Sheldon (2017)
Wyatt McClure Billy Sparks Billy Sparks See fewer	I See You (II) (2019)
Annie Potts Connie 'Meemaw' Tucker Connie 'Meemaw' Tucker See fewer	Ghostbusters (1984)
Jim Parsons Sheldon Cooper (voice) Sheldon Cooper (voice) See fewer	The Big Bang Theory (2007)
Wendie Malick Linda Hagemeyer Linda Hagemeyer See fewer	Waiting... (I) (2005)
Emily Osment Mandy McAllister Mandy McAllister See fewer	Hannah Montana: The Movie (2009)
Dan Byrd Pastor Rob Pastor Rob See fewer	Easy A (2010)
Rex Linn Tom Petersen Tom Petersen See fewer	Rush Hour (1998)
Doc Farrow Wayne Wilkins Wayne Wilkins See fewer	Young Sheldon (2017)
Zakary Risinger Danny Danny See fewer	Young Sheldon (2017)
Giovannie Espiritu Nurse Nurse See fewer	NCIS: Origins (2024)
Emily Bolt Wife Wife See fewer	Bookie (2023)
Preston Geer Husband Husband See fewer	Bookie (2023)
Grady Lee Richmond Wade (uncredited) Wade (uncredited) See fewer	The Ranch (2016)