Name	Known for
Iain Armitage Sheldon Cooper Sheldon Cooper See fewer	Scoob! (2020)
Zoe Perry Mary Cooper Mary Cooper See fewer	Young Sheldon (2017)
Lance Barber George Cooper Sr. George Cooper Sr. See fewer	Gangster Squad (2013)
Montana Jordan Georgie Cooper Georgie Cooper See fewer	Young Sheldon (2017)
Raegan Revord Missy Cooper Missy Cooper See fewer	Young Sheldon (2017)
Annie Potts Meemaw Meemaw See fewer	Ghostbusters (1984)
Jim Parsons Sheldon Cooper (voice) Sheldon Cooper (voice) See fewer	The Big Bang Theory (2007)
Craig T. Nelson Coach Dale Ballard Coach Dale Ballard See fewer	Coach (1989)
Mayim Bialik Amy Farrah Fowler (voice) Amy Farrah Fowler (voice) See fewer	Beaches (1988)
Wendie Malick President Hagemeyer President Hagemeyer See fewer	The American President (1995)
Drew Powell Roy Roy See fewer	Gotham (2014)
Doc Farrow Coach Wayne Wilkins Coach Wayne Wilkins See fewer	Saved Rounds (2019)
Jully Lee Chloe Chloe See fewer	S.W.A.T. (2017)
Sarah Jane MacKay Sally Sally See fewer	The Orville (2017)
Landen Beattie Jesse Jesse See fewer	Spiral Farm (2019)
Jeffrey J. Ayers Roadhouse Patron (uncredited) Roadhouse Patron (uncredited) See fewer	Stigmata (1999)
Portia D. Harris Diner Patron (uncredited) Diner Patron (uncredited) See fewer	Night Hawkes (2023)