Grey's Anatomy What a Difference a Day Makes (Season 5, Episode 22)
TV-14
TV Episode | 60 min | Drama, Romance

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Grey's Anatomy

What a Difference a Day Makes (Season 5, Episode 22)

TV-14

TV Episode | 60 min | Drama, Romance

A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey...See moreA car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey searching for the cause, and the results will change the outcome of the day. Written by layle See less

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Cast	+ Add Cast
33 cast members

Name	Known for
Ellen Pompeo Dr. Meredith Grey Dr. Meredith Grey See fewer	Grey's Anatomy (2005)
Sandra Oh Dr. Cristina Yang Dr. Cristina Yang See fewer	Killing Eve (2018)
Katherine Heigl Dr. Izzie Stevens Dr. Izzie Stevens See fewer	One for the Money (2012)
Justin Chambers Dr. Alex Karev Dr. Alex Karev See fewer	Grey's Anatomy (2005)
T.R. Knight Dr. George O'Malley Dr. George O'Malley See fewer	The Flight Attendant (2020)
Chandra Wilson Dr. Miranda Bailey Dr. Miranda Bailey See fewer	Grey's Anatomy (2005)
James Pickens Jr. Dr. Richard Webber Dr. Richard Webber See fewer	Grey's Anatomy (2005)
Sara Ramirez Dr. Callie Torres Dr. Callie Torres See fewer	Grey's Anatomy (2005)
Eric Dane Dr. Mark Sloan Dr. Mark Sloan See fewer	X-Men: The Last Stand (2006)
Chyler Leigh Dr. Lexie Grey Dr. Lexie Grey See fewer	Not Another Teen Movie (2001)
Kevin McKidd Dr. Owen Hunt Dr. Owen Hunt See fewer	Trainspotting (1996)
Patrick Dempsey Dr. Derek Shepherd Dr. Derek Shepherd See fewer	Grey's Anatomy (2005)
Jeffrey Dean Morgan Denny Duquette Denny Duquette See fewer	Watchmen (2009)
Jessica Capshaw Dr. Arizona Robbins Dr. Arizona Robbins See fewer	Valentine (2001)
Amy Gumenick Becca Wells Becca Wells See fewer	TURN: Washington's Spies (2014)
Roberto Urbina Jordan Jordan See fewer	Che: Part One (2008)
Robin Gwynne Becca's Mom Becca's Mom See fewer	The D.A. (2004)
Trent Gill David David See fewer	Greenberg (2010)
Mark Saul Intern Steve Intern Steve See fewer	Grey's Anatomy (2005)
Molly Kidder Intern Megan Intern Megan See fewer	Luckiest Girl Alive (2022)
Candice Afia Intern Laura Intern Laura See fewer	Grey's Anatomy (2005)
Mickey Maxwell Minister Minister See fewer	Grey's Anatomy (2005)
Amrapali Ambegaokar Intern Dani Intern Dani See fewer	Truth Be Told (2019)
Tymberlee Hill Intern Claire (as Tymberlee Chanel) Intern Claire (as Tymberlee Chanel) See fewer	Due Date (2010)
Winston Story Intern Leo Intern Leo See fewer	Brooklyn Nine-Nine (2013)
Joe Williamson Intern Pierce (as Joseph Williamson) Intern Pierce (as Joseph Williamson) See fewer	Black Bird (2022)
Payton Silver Dr. Knox Dr. Knox See fewer	Grey's Anatomy (2005)
Wayne Lopez Paramedic #1 Paramedic #1 See fewer	G.I. Joe: The Rise of Cobra (2009)
Shi Ne Nielson Paramedic #2 (as Shi Ne Neilson) Paramedic #2 (as Shi Ne Neilson) See fewer	Charmed (2018)
Mac Brandt Paramedic #3 Paramedic #3 See fewer	Lovecraft Country (2020)
Tim Chiou Paramedic #4 Paramedic #4 See fewer	The Company You Keep (2023)
Bokhee An Nurse Bokhee (uncredited) Nurse Bokhee (uncredited) See fewer	Grey's Anatomy (2005)
Jennifer Couch Dana (uncredited) Dana (uncredited) See fewer	AVH: Alien vs. Hunter (2007)