Name	Known for
Hugh Laurie Dr. Gregory House Dr. Gregory House See fewer	House (2004)
Lisa Edelstein Dr. Lisa Cuddy Dr. Lisa Cuddy See fewer	House (2004)
Omar Epps Dr. Eric Foreman Dr. Eric Foreman See fewer	House (2004)
Robert Sean Leonard Dr. James Wilson Dr. James Wilson See fewer	Dead Poets Society (1989)
Jennifer Morrison Dr. Allison Cameron Dr. Allison Cameron See fewer	House (2004)
Jesse Spencer Dr. Robert Chase Dr. Robert Chase See fewer	House (2004)
Anne Dudek Dr. Amber Volakis Dr. Amber Volakis See fewer	White Chicks (2004)
Edi Gathegi Dr. Jeffrey 'Big Love' Cole Dr. Jeffrey 'Big Love' Cole See fewer	StartUp (2016)
Peter Jacobson Dr. Chris Taub Dr. Chris Taub See fewer	House (2004)
Kal Penn Dr. Lawrence Kutner Dr. Lawrence Kutner See fewer	Harold & Kumar Go to White Castle (2004)
Olivia Wilde Thirteen Thirteen See fewer	Tron: Legacy (2010)
Carmen Argenziano Henry Dobson Henry Dobson See fewer	Identity (2003)
Andy Comeau Dr. Travis Brennan Dr. Travis Brennan See fewer	8 Heads in a Duffel Bag (1997)
Azura Skye Irene Irene See fewer	28 Days (2000)
Caroline Lagerfelt Connie Connie See fewer	Sweet Magnolias (2020)
Tom Wright Dr. Pilcher Dr. Pilcher See fewer	Daisy Jones & The Six (2023)
Scott Alan Smith Dr. Brady Dr. Brady See fewer	Mousehunt (1997)
Kenneth White Old Man Old Man See fewer	Fire in the Sky (1993)
Jerry Hauck Martin Martin See fewer	Matchstick Men (2003)
Bobbin Bergstrom Nurse Nurse See fewer	Volcano (1997)
Vince Deadrick Jr. Mr. Franklin (uncredited) Mr. Franklin (uncredited) See fewer	Romancing the Stone (1984)
Jose Vasquez Gang Banger (uncredited) Gang Banger (uncredited) See fewer	Selena (1997)