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| Series Cast Summary (27 of 754) (View more cast) | Episode Count | Year Range | STARmeter™ |

| Noah Wyle ... Dr. John Carter / ... | 255 | (1994-2009) | 1,051 |
 | Laura Innes ... Dr. Kerry Weaver / ... | 251 | (1995-2009) | 5,718 |

| Laura Cerón ... Nurse Chuny Marquez | 219 | (1995-2009) | 6,171 |

| Maura Tierney ... Nurse Abby Lockhart / ... | 190 | (1999-2009) | 1,526 |
 | Deezer D ... Nurse Malik McGrath | 188 | (1994-2009) | 16,357 |

| Goran Visnjic ... Dr. Luka Kovac / ... | 186 | (1999-2009) | 2,717 |
 | Yvette Freeman ... Nurse Haleh Adams | 185 | (1994-2009) | 17,186 |

| Anthony Edwards ... Dr. Mark Greene / ... | 182 | (1994-2009) | 2,285 |

| Eriq La Salle ... Dr. Peter Benton / ... | 173 | (1994-2009) | 5,459 |

| Emily Wagner ... Doris Pickman | 167 | (1994-2009) | 9,016 |

| Alex Kingston ... Dr. Elizabeth Corday / ... | 161 | (1997-2009) | 1,816 |

| Lynn A. Henderson ... Pamela Olbes | 148 | (1995-2009) | 17,931 |

| Sherry Stringfield ... Dr. Susan Lewis / ... | 143 | (1994-2009) | 3,923 |

| Abraham Benrubi ... Jerry Markovic | 141 | (1994-2009) | 4,546 |

| Mekhi Phifer ... Dr. Gregory Pratt / ... | 136 | (2002-2009) | 1,629 |

| Julianna Margulies ... Nurse Carol Hathaway / ... | 136 | (1994-2009) | 815 |

| Parminder Nagra ... Dr. Neela Rasgotra / ... | 130 | (2003-2009) | 2,730 |
 | Troy Evans ... Frank Martin / ... | 129 | (1994-2009) | 14,009 |

| Linda Cardellini ... Nurse Samantha Taggart / ... | 127 | (2003-2009) | 546 |

| Lily Mariye ... Nurse Lily Jarvik | 127 | (1994-2009) | 17,598 |

| Paul McCrane ... Dr. Robert Romano / ... | 126 | (1997-2009) | 6,338 |

| Ming-Na ... Dr. Jing-Mei Chen / ... | 118 | (1995-2004) | 856 |

| Montae Russell ... Dwight Zadro | 117 | (1995-2009) | 33,758 |
 | Scott Grimes ... Dr. Archie Morris / ... | 113 | (2003-2009) | 3,143 |

| Ellen Crawford ... Nurse Lydia Wright | 113 | (1994-2009) | 15,561 |
 | Conni Marie Brazelton ... Nurse Connie Oligario | 113 | (1994-2003) | 31,515 |

| George Clooney ... Dr. Doug Ross | 109 | (1994-2009) | 43 |
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